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SEROQUEL XR (AstraZeneca Pharmaceuticals LP) FDA Package Insert, Page 13 - Quetiapine (seroquel) is an atypical antidepressant drug used to treat bipolar disorder, depression, and schizophrenia. Seroquel (quetiapine) does not show up on a routine drug screen. Standard drug tests don't test for antipsychotics such as seroquel. The answer is no, taking seroquel will not cause you to fail a drug test for commonly tested substances such as opioids, cocaine, marijuana,. You should also read this: Test De Orina Negativo Y Estaba Embarazada
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