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Does Azo Treat Urinary Tract Infection (UTI)? Phenazopyridine How to - Azo, or phenazopyridine, is a medication used to relieve pain and discomfort. One of the critical concerns surrounding azo is its potential impact on urine tests used for. Phenazopyridine can interfere with certain laboratory tests (including urine tests. Yes, aso can affect your urine tests results. Azo won't have any affect on the urine test results, it only treats the. You should also read this: Reticulocyte Count Test