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Schematic of the two paper test strips and components. For the HE4 test - Use the he4 is an enzyme immunometric assay for the quantitative determination of he4 in human serum. Human epididymis protein 4 (he4) is a tumor marker useful in patients who have been treated for ovarian cancer. A change in serum he4 concentration of greater. Increase in human epididymis protein 4 (he4) suggests recurrence or disease progression, while a decrease suggests. You should also read this: What Is An Spep Test
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