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Wellbutrin vs. Generic Bupropion - Therapeutic use of bupropion appears to be the most frequent cause of false positive urine drug screens for amphetamines in our population. The extent of protein binding of the hydroxybupropion metabolite is similar to that. Cbd itself will not cause a false positive drug test,. Learn more about the drug's metabolism and detection. Yes, wellbutrin can potentially cause a false. You should also read this: Ar Test Answer

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