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Amitriptyline and topiramate no more effective than placebo in - For dot drug testing panels, the amitripyline will. The amount of time marijuana stays in your system can range from one to 90 days, depending on the test you take to measure it. Some places do test for tricyclics, which amitriptyline is a tricyclic, and some do not, but if you have a prescription for the drug, they cannot hold. You should also read this: 6 Mam Drug Test
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