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Saliva vs Urine Drug Tests What's the Difference? - Serum drug screens are okay but blood in the urine can. Yes, you can take a drug test during your period; Menstruation does not affect drug test results, as drug tests analyze substances in urine or. When you take a urine drug test while you are on your period, especially during the first three. Does not affect a drug test. You should also read this: What Is Anti Mullerian Hormone Test
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